Advancing African Genomics: Uganda Hosts Landmark AfSHG Conference

This week, Uganda is at the center of global genomics discussions as it hosts the 15th African Society of Human Genetics (AfSHG) Conference. This significant event aims to accelerate genomics research across Africa.

Taking place at Speke Resort Munyonyo from February 3rd to 7th, the conference has drawn over 300 leading scientists, policymakers, and industry experts from Africa and beyond. Themed “Harnessing Data Science and Artificial Intelligence for African Genomics,” the event seeks to bridge key research gaps through collaboration, technology, and policy innovation.

Organized by the MRC/UVRI and LSHTM Uganda Research Unit in partnership with Makerere University, the conference will explore how artificial intelligence (AI) and data science can revolutionize genomics research. This includes advancements in early disease diagnosis, precision medicine, and drug development tailored for African populations.

Professor Moffat Nyirenda, Director of the MRC/UVRI and LSHTM Uganda Research Unit, underscored the need for collaboration in advancing genomics research.

“The future of genomics in Africa depends on building strong and sustainable partnerships,” he stated. “This conference provides an invaluable platform for researchers, institutions, and policymakers to collaborate and drive innovation.”

With genomics research still in its early stages in Africa, the conference will focus on several key areas:

Genomic research on rare and common diseases to enhance early diagnosis and personalized medicine.

Ethical, legal, and social aspects (ELSI) of genomics, including fair data governance and Africa-led policy frameworks.

The role of AI and data science in genomics, unlocking new possibilities in disease prediction and drug development.

Strengthening research networks to accelerate discoveries and establish Africa as a leader in global genomics.

A major milestone of the event will be the launch of the Uganda Society for Human Genetics and Bioinformatics (USHGB). This initiative, led by early and mid-career genomics researchers, aims to strengthen local expertise, foster mentorship programs, and enhance regional collaboration in genomic and bioinformatics research.

Another highlight is the launch of KidneyGenAfrica, a cross-African partnership dedicated to advancing research and training in the genomics of kidney disease. The initiative brings together academic and research institutions from Africa, Europe, and the United States to expand expertise and resources for large-scale genomic analysis.

The MRC/UVRI and LSHTM Uganda Research Unit’s General Population Cohort—a database with over 35 years of rich linked data from southwestern Uganda—will be a key resource for KidneyGenAfrica. Researchers aim to identify genetic factors contributing to kidney disease in African populations, ultimately improving diagnosis, treatment, and prevention strategies.

Professor Segun Fatumo, Director of KidneyGenAfrica and Chair of the Conference, emphasized the transformative role of AI in genomics.

“This conference is not just about exchanging ideas—it’s a call to action for scientists, policymakers, and industry experts to harness artificial intelligence and unlock Africa’s genomic potential,” he said. “By doing so, we can develop medical treatments that are effective for all populations, regardless of ethnic background.”

The AfSHG Conference will also recognize outstanding contributions to genomics research in Africa. The event features interactive poster presentations, networking sessions, and affiliate society meetings to foster interdisciplinary collaboration and inspire the next generation of African genomic scientists.

Founded in 2003, the African Society of Human Genetics (AfSHG) is dedicated to equipping African scientists and policymakers with the tools and knowledge necessary to advance genomics research. The organization also works to amplify African researchers’ contributions on the global stage. With Uganda hosting this year’s conference, the event is expected to shape the future of genomics on the continent, positioning Africa at the forefront of scientific discovery and innovation.